Goodbye Sweat Struggles.
Hello Confidence.

Prescription-strength treatment for excessive sweating. Clinician visit, medication, & shipping included. No hidden fees & no insurance required.
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2 mins • FREE online visit
Sweat-specialized providers
100% online, no wait times
No insurance needed
US-based pharmacies
Free shipping & cancel anytime
discover your treatment

EverdryRx Gel

1.7oz | 50ml
EverdryRx Gel is a prescription-grade treatment developed with expert dermatologists to deliver targeted, full-body sweat control. Fast-absorbing, invisible on skin, aluminum-free, and crafted for the way you actually live.
Starting at Just $55/month
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What’s Inside + How it Works

Oxybutynin 8%: A prescription treatment used to treat excessive sweating (hyperhidrosis). By blocking the action of acetylcholine on sweat glands, it helps reduce sweat production in targeted areas, offering effective, localized control.

  • Formulated with our Twofold EverdryRx Base to penetrate the skin and deliver targeted sweat control.
  • Blocks acetylcholine signals to reduce sweat production at the source.
  • Fast-absorbing, clear gel that applies easily and leaves no residue or visible trace on the skin.
  • Dermatologist-crafted with powerful, targeted ingredients for full-body sweat control.

Freshly compounded at our partner pharmacy, ensuring maximum efficacy with every application.

How to Apply
  • Before Applying:
    • Wash your hands with warm water and soap.
    • Ensure the area you’re treating is clean, completely dry, and at room temperature.
  • When to Apply:
    • Apply once daily in the evening, or as directed by your provider.
    • For optimal results, apply just before bed.
  • How to Apply:
    • Dispense 2–3 pumps of gel per treatment area onto clean fingertips.
    • Gently apply a thin, even layer over the entire treatment area. Do not rub aggressively.
    • Allow the gel to dry completely before covering with clothing.
    • Do not wash the treated area for at least 4 hours after application.
Keep in Mind
  • For External Use Only. Keep away from eyes, mouth, and nose. If accidental contact occurs with eyes, mouth, or broken skin (cuts, scrapes, burns), rinse immediately with water.
  • Avoid Sensitive Areas. Do not apply to broken, irritated, or sensitive skin (e.g., near eyes, nose, or mouth).
  • Wash Hands After Use to prevent accidental transfer of the product to unintended areas.
  • Adjust Based on Comfort. Monitor for any side effects like dryness or irritation and reduce frequency if needed.
  • Storage: Keep the product in a cool, dry place away from direct sunlight.
Free Online Consult
Free Expedited Delivery
Only Pay If Approved
Prescription-Strength Care
Formulated By Experts
HOW IT WORKS

The easiest way to finally get
(and stay) dry.

STEP 1

Complete our 2 minute online quiz

Answer a few questions about your symptoms and health goals so we can get to know you better.
STEP 2

Get a custom treatment plan

Within 24 hours, a medical provider, specialized in sweat, will review your information and create a plan tailored to you.
STEP 3

Receive your treatment

Your medication ships FREE and fast, plus unlimited provider follow-up care and messaging, if approved for treatment.
OUR GROWING COMMUNITY

Real stories, real results.
See the difference for yourself.

I didn’t know my hands could feel like this!

I've had sweaty palms since I was a teenager and can't remember the last time I shook someone's hand without feeling severe anxiety... now I don't even have to worry about it. I wish I had this product ten years ago!
Sarah S.
Verified TRIAL USER
Before
After

No more shirt changes throughout the day

I used to bring extra shirts to the office, but now I can wear the same one all day. I’ve been using it nightly without side effects, and it’s gentler on my skin than any antiperspirant I’ve tried (plus it’s aluminum-free).
Sebastian R.
Verified TRIAL USER
Before
After

Nothing slips out of my hands anymore!

I could never hold ANYTHING - my phone, the steering wheel, pens - all slipped through my hands. Sweating made my everyday feel unnecessarily difficult. Thanks to Twofold for actually seeing this as a problem and delivering a solution that works!
Jennifer N.
Verified TRIAL USER
Before
After

I can wear grey again

I can actually wear normal clothes again instead of just black or multiple coats and cardigans to hide my pit stains. I feel like I’m getting my life back now. Know that I’ll be a lifelong fan and user.
Gaby L.
Verified TRIAL USER
Before
After

Dry and less smelly feet

I can’t believe how well this worked. It took 6 nights, but I finally woke up and my feet were completely dry - no sweat at all. It’s such a different feeling than I’m used to and while I do sweat a little still, it’s nothing like it used to be.
Phil F.
Verified TRIAL USER
Before
After

24/7 care, by those who know sweat inside and out

Twofold was built with medical specialists who live and breathe sweat care. That means targeted treatment, meaningful follow-up, and support that actually feels supportive.
Let's compare

How we stack up

Cost
No Need For Insurance
Time To Get An Appointment
Number Of Visits To Get Treatment
24/7 Access To Sweat Specialists
Hyperhidrosis Expertise
Starts at $50 (Includes Free Consult with a Sweat Specialist*)
Same Day
1 (Everything Online)
Telemedicine Providers
$75-$150/Visit (Consultation Fee Extra)
3-7 Days
2-3
In-Person Dermatology Visits
$150-$400/Visit (Consultation Fee Extra)
Week to Months
4+ (Consult, Referral, Follow-up, Prescription Pick-up)
Limited
24/7 Doctor Access
Prescription Strength
Treats Multiple Sweat Zones
Aluminum-Free
One Tablet for Full-Body Sweat Control
Who It’s For
Where It Works
How Long It Lasts
Use From Home?
How It Feels
Cost
Time It takes
Mild to Severe Hyperhidrosis
Specific Zones
Ongoing with Continued Use
Non-Invasive
$$
A Few Minutes a Day
Antiperspirant
Normal Sweating, Mild Cases
Limited to Underarms, Feet or Palms
Ongoing with Continued Use
Non-Invasive
$
A Few Minutes a Day
Botulinum Toxin Injections
Moderate Hyperhidrosis
Targeted Areas
4-6 Months
Slightly Invasive
$$$
Requires Multiple Visits
Iontophoresis
Moderate Hyperhidrosis
Targeted Areas
Short-Term
Non-Invasive
$$$
Requires Weekly Sessions
MiraDry
Moderate Hyperhidrosis
Underarms Only
Permanent
Slightly Invasive
$$$
One Appointment with Downtime
Surgery
Severe Hyperhidrosis
Depends on Procedure
Permanent
Involves Surgery
$$$$
Surgery + Recovery
Clinically Proven
Easy To Use
Full Body Relief
Cost
Invasiveness
$$
Non-Invasive
Deodorants
Herbal Remedies
Supplements
$
Non-Invasive
Non-Invasive
Non-Invasive
Requires Needles
Acupuncture
$-$$
Hypnosis
$
$$$
$$$
Non-Invasive
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FAQ

Still have questions?

Check out our FAQs or email us at hello@itstwofold.com
We aim to get back to you within 24 hours!

What is Twofold?

Twofold is a virtual sweat clinic dedicated to helping people manage their hyperhidrosis, or excessive sweating. We provide treatment plans designed by licensed providers to address excessive sweating.
Twofold is all about making expert sweat care simple, effective, and accessible—delivered straight to your door without the need for in-person visits.

What's the process to get care with Twofold?

Twofold simplifies the process of managing hyperhidrosis with personalized care:

  1. Start with an Online Consultation
    Complete a quick, secure questionnaire about your symptoms, medical history, and treatment goals.
  2. Receive Your Treatment at Home
    If approved by your Twofold provider, your treatments will be compounded and shipped directly to your door in discreet packaging—no need for in-person visits.
  3. Ongoing Support
    You’ll have unlimited access to your care team for follow-up questions or adjustments to your treatment plan, all through the Twofold portal.

When will I notice a difference, and how long will the results last?

It usually takes about 4 weeks of daily use to see full, consistent results — so don’t worry if it feels slow a first. Many people will notice changes within their first 1–2 weeks, and it should keep improving from there. Consistent use of your prescribed medication is key to achieving and maintaining the best results. Individual response times can vary based on the severity of your hyperhidrosis and the area being treated.

Is this treatment FDA-approved and supported by science?

Oxybutynin, the primary ingredient in our treatment, is FDA-approved for several medical uses, but its use for treating hyperhidrosis is considered "off-label" in the U.S. Off-label prescriptions are a common and legal practice used when providers determine that a treatment is medically appropriate based on a patient's needs.

While oxybutynin's use in hyperhidrosis is off-label, it's widely prescribed by dermatologists due to its efficacy in reducing excessive sweating. Many studies have demonstrated the safety and efficacy of oxybutynin, and it has become a well-established treatment among specialists in the field. Our treatment plans are informed by existing research and customized by licensed providers to ensure you receive the best possible care.

How much does treatment cost, and is it covered by insurance?

Twofold offers quarterly subscription-based treatment plans, at $150 for 3 months of treatment.

Shipping is always free, and there are no hidden fees.

Currently, Twofold does not accept insurance. This allows us to provide greater transparency without surprise costs, copays, or hidden fees.