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Oxybutynin 8%: A prescription treatment used to treat excessive sweating (hyperhidrosis). By blocking the action of acetylcholine on sweat glands, it helps reduce sweat production in targeted areas, offering effective, localized control.
Freshly compounded at our partner pharmacy, ensuring maximum efficacy with every application.
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Twofold simplifies the process of managing hyperhidrosis with personalized care:
Hyperhidrosis is a medical condition that causes excessive sweating, up to 4–5 times more than the body needs to regulate temperature. It can affect specific areas like the underarms, hands, feet, or face (localized hyperhidrosis), or occur all over the body (systemic hyperhidrosis). For many people it's more than a physical issue; it affects confidence, comfort, and daily life.
Oral medication works throughout the body, making it a good fit for generalized sweating or when multiple areas are affected. Topical treatment can be applied almost anywhere it's needed, including the underarms, hands, feet, face, back, chest, and groin. The scalp can be harder to treat topically depending on hair length and density, so an oral option may be worth discussing with your provider. Always follow your provider's guidance on where to apply your treatment.
Oxybutynin belongs to a class of medications called anticholinergics. It works by blocking acetylcholine, a neurotransmitter that signals sweat glands to produce sweat. By reducing those signals, it decreases sweat production in the treated areas.
We currently ship to all states except West Virginia, Kansas, New Mexico, Alabama, and Arkansas. All orders ship free in discreet packaging, and your first shipment typically arrives within 2–5 business days after your treatment plan is approved.
Yes. Log into your Twofold account, select My Treatments, choose the treatment, then select Manage → Take a break and follow the prompts. Canceling stops future refills; a refill already processed by the pharmacy may not be cancellable. Questions? Email hello@itstwofold.com.
Excessive sweating is primarily caused by an overactive nervous system: in people with hyperhidrosis, the sweat glands receive more signals than necessary from the nerves that control sweating. Primary hyperhidrosis is often linked to genetics and typically affects specific areas like the hands, feet, underarms, or face, usually starting in adolescence or early adulthood. Secondary hyperhidrosis is caused by another condition, such as thyroid disorders, diabetes, infections, or hormonal changes, or is a side effect of certain medications. Triggers like stress, anxiety, spicy foods, or heat can make sweating worse in both types.
Twofold is designed for people experiencing excessive sweating, whether it's systemic or localized. You may be eligible if you are 18 years or older, struggle with excessive sweating that impacts your daily life, and have no medical conditions or medications that might conflict with treatment. A licensed provider will review your symptoms and medical history during your online consultation to determine whether treatment is right for you.
No in-person visits are required. All consultations and follow-ups are conducted securely online through your patient portal. You complete a quick online questionnaire about your symptoms and health history, a licensed provider reviews it, and if treatment is right for you, it ships to your door. You'll also have unlimited messaging with your care team for follow-up questions or adjustments to your plan, all without an appointment or waiting room.
